Callum Hudson became the first Chelsea player to be both substituted on and then subbed off in the same league game this 20/21 season earlier today (February 20, 2021) against Southampton.
Hudson Odoi was subbed on for Tammy Abraham at half time and just thirty minutes later, Tuchel subbed him off for Hakim Ziyech.
Hudson Odoi vs Southampton February 2021
46′ CHO comes on for Abraham
76′ CHO replaced by Ziyech
Interestingly before today, CHO was also the last Chelsea player to be subbed on and off in the same league game- it happened to him in the 2-1 win over Watford in December 2018 (he replaced Pedro in the 43rd minute & was taken off for Emerson in the 85th minute)